International Conference

II ‘Total-Nanosafe’


6-8 NOVEMBER 2024

Venue
BRAGA - PORTUGAL

INL - International Iberian Nanotechnology Laboratory

The II ‘Total-Nanosafe’ International Conference is bringing experts in different fields related to the use of nanomaterials, nanotechnology and how these are related to different aspects of safety, regarding health and the environment.

We will have experts talking about nanotoxicology, organ-on-a-chip, cheminformatics, public health and the environment, among the main topics.

| THANK YOU!

Thank You Note to All Participants of the Total-Nanosafe II Conference

Dear Participants,

On behalf of the Sinfonia Project team, We would like to express our sincerest gratitude to each of you for attending the II ‘Total-Nanosafe’ International Conference. Your presence, insights, and dedication have made this event a true celebration of progress, innovation, and collaboration in nanosafety.

The success of this conference would not have been possible without the vibrant exchange of ideas, the groundbreaking presentations, and the invaluable expertise that each of you brought to Braga. Together, we explored critical advancements in nanotoxicology, cutting-edge safety models, and the environmental impact of nanomaterials—setting the stage for a future of safer, more sustainable nanotechnology.

Ernesto Alfaro-Moreno, Head of Nanosafety at INL and Coordinator of the LEARN Project said, “The Total-Nanosafe II Conference was an incredible opportunity to bring together some of the brightest minds in the field. Leading this initiative was a privilege, and I must say, the experience was even more engaging, enjoyable, and challenging than I had anticipated. A heartfelt thank you to all participants, speakers, and members of the Sinfonia Project Advisory Board.

We hope you left the conference with new connections, inspiration, and collaborative opportunities that will shape the future of nanosafety. Thank you once again for being an essential part of this remarkable event. We look forward to seeing where this journey takes us next—together.

Warm regards,

The Sinfonia Project Team


| 7 November, 2024

| 8 November, 2024

| ABOUT

The II ‘Total-Nanosafe’ International Conference is a flagship event that gathers world-renowned experts to explore the vital connections between nanomaterials, nanotechnology, and their impact on human health and the environment. 

This year’s conference will focus on pioneering topics such as nanotoxicology, advanced models like organ-on-a-chip for nanosafety testing, in vitro-in vivo bridging models, in silico approaches, and the environmental effects of nanomaterials. Attendees will gain insights into the latest innovations and trends shaping the future of nanosafety.

With an emphasis on fostering collaboration and driving innovation, this conference provides a comprehensive view of the current state-of-the-art in nanosafety. Participants will have the opportunity to engage with leading researchers, industry professionals, and policymakers, expanding their networks and setting the stage for groundbreaking partnerships.

Whether you're looking to lead in nanotechnology safety or discover new collaboration opportunities, this conference offers a unique platform for knowledge exchange and idea generation, pushing the frontiers of safe and sustainable nanotechnology development.


| Meet the Speakers

Our distinguished speakers will delve into critical topics such as nanotoxicology, organ-on-a-chip technology, cheminformatics, and their implications for public health and environmental safety.

Through their groundbreaking research and insights, they will shed light on the safe use of nanomaterials and the profound impact these advancements have on our health and the environment. Join us as we discuss the cutting-edge developments shaping the future of nanotechnology.

  • A. Başak Engin

    PhD
    Gazi University, Turkey

  • Ana Isabel Bourbon, Staff Researcher

    Ana Isabel Bourbon

    Ana Isabel Bourbon, Staff Researcher, Pastrana Research Group, INL, Portugal

  • Ana Ribeiro Staff Researcher

    Ana Ribeiro

    Staff Researcher, Alfaro-Moreno Research Group, INL, Portugal

  • Ben Maoz

    Faculty Member at the Sagol School of Neuroscience and the Department of Biomedical Engineering at Tel Aviv University, Israel

  • Dario Greco

    Professor of bioinformatics at the Faculty of Medicine and Health Technology, Tampere University, Finland

  • Ernesto Alfaro-Moreno

    Head of Nanosafety at INL and Coordinator of the LEARN project, Portugal

  • Eugenia Valsami-Jones

    Professor of Environmental Nanoscience at the University of Birmingham, UK

  • Filipa Lebre

    Research Fellow, Alfaro-Moreno Research Group, INL, Portugal

  • Fiona Murphy

    Lecturer of Immunology and Pharmacology at the Strathclyde Institute of Pharmacy and Biomedical Sciences, Scotland

  • Irini Furxhi

    Marie Skłodowska-Curie Postdoctoral Fellow at CNR-ISSMC, Italy

  • Javier Ramón Azcón

    ICREA professor at the Institute for Bioengineering of Catalonia (IBEC), Spain

  • Laura Rodriguez-Lorenzo, Staff Researcher,

    Laura Rodriguez-Lorenzo

    Laura Rodriguez-Lorenzo, Staff Researcher, Espiña Research Group, INL, Portugal

  • Laure-Alix Clerbaux

    Senior Researcher, Institute of Experimental and Clinical ResearchSenior Researcher, Institute of Experimental and Clinical Research, UCLouvain, Belgium

  • Michael González-Durruthy Research Fellow

    Michael González-Durruthy

    Michael González-Durruthy, Research Fellow, Alfaro-Moreno Research Group, INL, Portugal

  • Miguel Xavier Staff Researcher

    Miguel Xavier

    Staff Researcher, Abalde-Cela Research Group, INL, Portugal

  • Nivedita Chatterjee, Staff Researcher

    Nivedita Chatterjee

    Nivedita Chatterjee, Staff Researcher, Alfaro-Moreno Research Group, INL, Portugal

  • Pauliina Damdimopoulou

    ssociate Professor in Perinatal and Reproductive Toxicology at Karolinska Institutet, Sweden

  • Sean Kelly

    Senior Project Manager & Interim Director General NIA, England

  • Ulla Vogel

    Honorary Professor at the Technical University of Denmark and Honorary Doctor at Lund University, Sweden

  • Vânia Vilas-Boas  Research Fellow

    Vânia Vilas-Boas

    Research Fellow, Research Fellow • Alfaro-Moreno Research Group, INL, Portugal


| Agenda

Wednesday, November 6

18h00-20h00 Check-in and Welcome Cocktail

Thursday, November 7

09h00 -10:00 Keynote Speaker

Ulla Vogel, “The toxicology of inhaled nanoparticles and examples of risk assessment and regulation”, Professor National Research Centre for the Working Environment, Denmark. Expert in the health-damaging effects of dust, particles and chemicals in the working environment, particularly concerning cancer, cardiovascular disease and fertility. 

10h00-10h20 Vânia Vilas-Boas, Effects of silver nanoparticles on lung-barrier function: studies on a new human-based in vitro model, Research Fellow • Alfaro-Moreno Research Group, INL, Portugal

10h20-10h40 Filipa Lebre, “At the crossroad of cell signalling and safety”, Research Fellow • Alfaro-Moreno Research Group, INL, Portugal

10h40-11h00 Coffee-break

11h00-11h20 Sónia Fraga, “Assessment of engineered and incidental nanoparticles’ hazard for human health based on in vitro testing – the impact of the experimental approach”, Coordinator of the Chemicals and Advanced Materials – Safety and Health group of the Laboratory for Integrative and Translational Research in Population Health (ITR), Portugal

11h20-11h40 Ana Teresa Reis, “Beyond single exposures: understanding toxicity across different cell lines and endpoints after exposure to complex mixtures of nanomaterials and potentially toxic elements”, Research Line: L3 - Genetic, Behavioural and Environmental Determinants of Health and Disease of the Laboratory for Integrative and Translational Research in Population Health (ITR), Portugal

11h40-12h00 Basak Engin, The Effect of Peripheral Macrophages on Silver Nanoparticles Induced Neuronal Toxicity in Insulin Resistant State; Gazi University, Faculty of Pharmacy, Department of Toxicology, Turkey

12h00-12h20 Félix Carvalho, “Intestinal Inflammatory Response Induced by Voluntary Oral Ingestion of Silver Nanoparticles in Mice”, Full Professor of Toxicology, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy at University of Porto, Portugal

12h20-13h30 Lunch

13h30-13h50 Ben Maoz, Organs-on-a-Chip: A New Tool for Studying Human Physiology”, Sagol School of Neuroscience and the Department of Biomedical Engineering at Tel Aviv University, Israel

13h50-14h10 Ana Ribeiro, “Skin-on-chip system for safety assessment of nanomaterials”, Staff Researcher • Alfaro-Moreno Research Group, INL, Portugal

14h10-14h30 Rodrigo De Vecchi, “Use of 3D models for Cosmetics Safety and Efficacy”; Leading research projects L´Oréal Research & Innovation, France

14h30-14h50 Miguel Xavier,Advanced 3D models for metastatic breast cancer research”, Staff Researcher Abalde-Cela Research Group, INL, Portugal

14h50-15h10 Javier Ramón Azcón, “A new tool for studying human physiology”, Group Leader / ICREA Research Professor, Spain

15h10-15h30 Tim Nawrot, “Translocation of Ambient Black Carbon to Different Organs: Implications for Accelerated Ageing”; Head of the environmental and molecular epidemiology research unit at Hasselt University, Belgium

15h30-15h50 Coffee-break

15h50-16h10 Host: Monique Groenewold, “Safe and Sustainable Advanced and Innovative Materials 2024-2030”, Senior policy advisor and coordinator Dutch Institute for Public Health and Environment (RIVM), Netherlands

16h10-17h00 Short Oral Presentations

  • “In vitro evaluation of differently charged gold nanoparticles in neuronal cells: analysis of cell cycle, apoptosis and DNA damage”, Lucía Ramos-Pan, A Coruña University, Spain

  • “Assessing the Potential Toxic Effects of Platinum Nanoparticles Using Neuronal Cells and Drosophila melanogaster”, Assia Touzani, A Coruña University, Spain

  • Assessing the safety of technical kraft lignin and its nanoparticles to Pacific oyster (Magallana gigas) gametes and early life stages”, Ana Carvalhais, Aveiro University, Portugal

  • MixIng-Tox: investigating the combined effects of nanomaterials and potentially toxic elements in food products - discover the project and collaborate”, Ana Teresa Reis, Institute of Public Health, Porto University, Portugal

  • Numerical model to study the fate of engineered nanoparticles in marine water”: Carla Lopes, Institute of Marine Research (IIM-CSIC), Spain

Friday, November 8

09h00-10h00 Keynote Speaker

Ernesto Alfaro-Moreno, “Sinfonia: 4 years of INL integration in the "concert" of Nanosafety”, Head of Nanosafety at INL and Coordinator of the LEARN project.

10h00-10h20 Laure-Alix Clerbaux, “AOPs to support assessment of food nanomaterials' toxicity on gut microbiota and intestinal barrier integrity”, Senior Researcher, Institute of Experimental and Clinical ResearchSenior Researcher, Institute of Experimental and Clinical Research, UCLouvain, Belgium

10h20-10h40 Michael González-Durruthy, “Computational Nanotoxicology of Complex Nano-Mixtures”, Research Fellow • Alfaro-Moreno Research Group, INL, Portugal

10h40-11h00 Coffee-break

11h00-11h20 Irini Furxhi, “From Creation to Conclusion: Unlocking Insights at Every Stage of the Nanomaterial Journey, Marie Skłodowska-Curie Postdoctoral Fellow at CNR-ISSMC, Italy

11h20-11h40 Dario Greco, “Integrated approaches in toxicology and pharmacology: from nanosafety to SSbD and One Health”, Professor, Faculty of Medicine and Health Technology Tampere University, Finland

11h40-12h00 Pauliina Damdimopoulou, “Pollutants and Female Reproduction”, Senior Lecturer in Reproductive and Perinatal Toxicology & Research Group Leader Karolinska Institutet, Sweden

12h00-12h20 Nivedita Chatterjee, “C. elegans as a Reliable Tool for Assessing Neuronanosafety: Studies on Diesel Exhaust Particles and Silver Nanoparticles”, Staff Researcher • Alfaro-Moreno Research Group, INL, Portugal

12h20-13h30 Lunch

13h30-13h50 Fiona Murphy, “Exploring the Potential of Galleria Mellonella as an in vitro-in vivo Bridging Model for Particle Toxicology” Lecturer of Immunology and Pharmacology Strathclyde Institute of Pharmacy and Biomedical Sciences, England

13h50-14h10 Ana Isabel Bourbon, “Development of PLA multilayer film incorporating cellulose nanocrystals: physicochemical characterization and safety evaluation”, Staff Researcher • Pastrana Research Group, INL, Portugal

14h10-14h30 Blanca Rollón, “Safe by process design (SbPD): practical lessons learned from case studies”, Project Technician, ITENE, Spain

14h30-14h50 Laura Rodriguez-Lorenzo, “Analysis of the smallest small microplastics (≤ 10 µm) and nanoplastics in natural water”, Staff Researcher • Espiña Research Group, INL, Portugal

14h50-15h10 Coffee-break

15h10-15h30 Sean Kelly, “From Innovation to Implementation: How to make your nanosafety research regulatory relevant”, Senior Project Manager & Interim Director General NIA, England

15h30-16h30 Keynote Speaker

Eva Valsami-Jones, Nanomaterials: the Known Unknowns in Materials Safety; School of Geography, Earth and Environmental Sciences at the University of Birmingham, Chair in Environmental Nanoscience, Director of FENAC, England. Expert on the interaction of a variety of carbon- and metal-based nano-objects with biota in vitro and in vivo and pioneer in novel methods of labelling nanomaterials.

16h30-16h45 Nanosfety Book Presentation and Closing of the event


| Abstract Submission

Abstract submissions for the II TOTAL - NANOSAFE International Conference are now closed. Participants will be contacted via the provided email with the committee's decision. We appreciate your interest!
Take an active part in this International Conference!

CONFERENCE TOPICS:

  • Nanotoxicology (including immunotoxicity, genotoxicity and epigenetics)

  • Advanced models (including Organ-on-a-chip) to test nanosafety)

  • Bridging models between in vitro-in vivo

  • In silico approaches

  • Environmental impact of nanomaterials

Note: The ‘Total-Nanosafe’ online Poster Session will be open for the duration of the conference, providing information on research related to the topics of this unique conference. Poster presentations will be available to conference attendees in a PDF format.


| Contact Us

events@inl.int
International Iberian Nanotechnology Laboratory
Avenida Mestre José Veiga s/n, 4715-330 | Braga, Portugal